Enzymes are proteins that occur in living organisms that make it possible to carry out metabolic reactions. There are different types of enzymes: digestive, metabolic and dietary, although the deficit of digestive enzymes is the most affects the digestion, absorption and utilization of nutrients.

Functions of enzymes

Each group of enzymes has some functions in the body. Digestive enzymes allow the body to absorb nutrients in foods and give benefit in the diet. Metabolic enzymes contribute to the elimination of toxins, as well as assist in the smooth functioning of the immune system, while the enzymes help to dietary different digestive processes take place and contribute to the proper functioning of other enzymes.

Causes of deficiency

The lack or destruction of enzymes may be due to the existence of certain diseases, the aging process itself or digestive disorders that primarily affect the stomach and intestine. you do not need to worry because now there is florazyme dietary enzyme that can help your digestion problem

Florazyme digestive aid

FloraZyme Digestive Aid delivers a powerful partnership of beneficial flora and enzymes, together in a single convenient capsule.

Florazyme Benefits:

CLICK HERE to learn more

• florazyme helps alleviate occasional acid indigestion and gas
• florazyme Promotes normal digestive transit time
• Supports thorough digestion and nutrient absorption

If this is a MUST HAVE product, be sure to ORDER NOW and get the best price of Florazyme.

Definition

Steinert syndrome (Myotonic Muscular Dystrophy MMD) is a hereditary progressive muscle slowly and gradually, usually manifested in adulthood. It is characterized by:

• Myotonia or difficulty muscle relaxation. There is a sustained muscle contraction.
• Slow but progressive muscular atrophy.
• Systemic manifestations.

The earlier the disease occurs, the greater the degree of severity.

One form of early onset is known as congenital myotonic dystrophy, which occurs in babies born to parents who have the adult form and has not yet manifested or made very light. The congenital form is the most severe form of Myotonic Muscular Dystrophy. Normally, the mother has the disease, although their symptoms are so mild that it has not detected.

Mothers can also transmit the adult form, men with myotonic dystrophy when they have children, they can also inherit the disease, but usually occurs in adulthood.

Myotonic Muscular Dystrophy Causes

It is a systemic disease that is inherited as an autosomal dominant through the mother, which means that only one defective gene is needed to cause symptoms of the disease. Therefore, if one parent has the disease, every child of that person will have a 50 percent chance of inheriting the gene that causes the MMD.

If you pass the gene is almost certain that the child will develop the disease and will often be more severe in the child than the father.

In 1992 it was discovered that people with MMD is an area of DNA on chromosome 19 that is larger than it should be. The genetic defect is in a part of “untranslated” which is an area of DNA that does not use the cell to manufacture proteins. It was found that the expanded section of DNA on chromosome 19 was extended further when transmitted from father to son. The researchers found that this explained the observed phenomenon in the MMD, where children are most affected by the disease than their parents.

Scientists are trying to discover how and why there are so many myotonic dystrophy symptoms and could be extended to the area affect the operation of more than one gene.

Myotonic dystrophy Symptoms vary greatly from one person to another, which may occur:

Myotonia

This is a difficulty for relaxation after a voluntary muscle contraction or provoked. The contractions are painful and are not causing the patient’s disability.

Muscle weakness

In the evolution of the disease appears muscle weakness, causing disability, due to degeneration of muscle fibers. It occurs primarily in the facial muscles and distally in the lower extremities.

The weakness of the muscles of the face gives them a characteristic expression:

• Smile inverted.
• Sunken cheeks.
• Ptosis (drooping eyelid).

Usually no cause can grasp objects and hard as they do weaken the muscles that raise the foot when walking, they collapse and results in smoothly. Some people compensate by lifting the foot from the knee walking “step up”. In fact, the use of canes and other aids are more useful.

There are also various devices that hold the hand in a position to use the keyboard or write and compensate for the weakness of the muscles of the wrist or hand.

The weakness may also occur at the level of the muscles of the esophagus, stomach, intestinal and uterine.

Myotonic dystrophy Symptoms Systemic manifestations

Heart

• Involvement of the myocardium that can cause heart failure.
• Involvement of cardiac valves.
• Commitment Ventilatory by many factors.

Symptoms that can be appreciated are: fainting, lightheadedness and dizziness.
Involvement of respiratory muscles and throat

• It can affect the respiratory muscles including the diaphragm.
• Difficulty coughing, which can accumulate secretions.
• Restrictive lung abnormalities.
• Obstructive Sleep Apnea.

It can deprive the body of needed oxygen, so many almost always dream

• Sleep apnea: breathing stops for a few seconds or even minutes while sleeping.
• Swallowing problems, the person may drown or “swallowing the wrong way.” Food or drink passing into the windpipe instead of the esophagus (the throat to the stomach). Vomiting can be very dangerous to pass the stomach contents into the lung.

It may be useful at night using a portable ventilator to compensate for the weakness of the muscles controlling breathing and altered brain on respiration.

Gastrointestinal: in 80% of patients

• Weakness of the muscles of the throat with difficulty swallowing.
• Delayed gastric emptying.
• Pseudobstruction intestine. Diarrhea and constipation.
• Higher incidence of cholelithiasis (gallstones).
o Difficulty digesting fatty foods.
o Pain in right upper abdomen.

Other

• Cataracts develop almost everyone.
• Alterations of the endocrine apparatus hypothyroidism, testicular atrophy, impaired glucose metabolism, including diabetes mellitus.
• Mental retardation. Many people have labeled those affected by myotonic dystrophy as slow, apathetic or dull. Recall that the disease affects a very variable. However, mental disability is rare in the adult form.

They often need more sleep than others, and suggests there may be anomalies in those parts of the brain that determine the rhythm sleep / wake, which together with respiratory distress worsens.

The weakness of the facial muscles and drooping eyelids are added to the impression of “dumb” you can have these people.

Anesthesia

There is a high incidence of complications and even death with general anesthesia, even with a mild grade myotonic muscular dystrophy. If you have to undergo surgery, make sure you are aware of their condition the surgical team.

Also very variable, is characterized by:

• Generalized hypotonia. The child takes the typical posture of “open book”, poor spontaneous motility and decreased reflexes. There is no myotonia characteristic of the adult.
• Respiratory failure.
• Difficulty sucking and swallowing.
• Skeletal deformities: ribs thin, deformed feet (probably due to abnormal muscle development during pregnancy, etc.).
• Bruising.
• Edema.
• Mental retardation in late lactation. It is not always, and when it does appear to be due to abnormal development of certain parts of the brain caused by genetic abnormalities. It has also been suggested to be due to the high incidence of complications during childbirth that occurs in the affected mother. The medical team that treats the mother should be aware of this situation.

Presents an autosomal dominant, but when it appears in newborn’s mother is always the affected parent. Because many adults are unaware of their disease is very difficult diagnosis.

Molecular genetic techniques allow diagnosis of the disease and the possibility of offering genetic counseling to families.

It can be diagnosed during the first trimester of pregnancy through chorionic villus.

Congenital Myotonic Dystrophy Diagnosis

Diagnosis is mainly clinical.

Physical examination

A physician with expertise in neuromuscular disorders can be diagnosed with the disease relative ease. Other times may be the ophthalmologist who appreciates the falls and suspected diagnosis.
A teenager or adult usually has a characteristic appearance, along with other symptoms the doctor will ask. Some say that his parents had muscle problems.

Problems with the fists relax or release a tool, which are signs of myotonia.

To confirm the diagnosis is made by direct analysis of mutation: molecular analysis, which is indicated do in the following circumstances:

• Confirmation of clinical diagnosis.
• For detection of carriers without symptoms who belong to a family history of the disease.
• Prenatal diagnosis.

Congenital myotonic dystrophy:

Major Criteria

• Hypotonia.
• Myopathic facies.
• Muscular atrophy.
• Breathing difficulties.
• Feeding difficulties.

Additional criteria must be four

• Skeletal deformities.
• Elevation of the diaphragm.
• Ribs thin.
• Bruising.
• Edema.
• Dilated lateral ventricles.
• Anal sphincter insufficiency.
Confirmation is established by additional tests, neurological study, muscle biopsy and / or genetic study

Prognosis

The determining factor is the age of onset of the disease.
Adolescents and children with symptoms of myotonic dystrophy can “overcome” many aspects of the disease associated with muscle weakness to grow and mature. Mental retardation does not improve, but these children can learn if given the proper tools and environment.

Unfortunately, despite initial progress during childhood, all children with congenital myotonic dystrophy develop the adult form.

Treatment

At present, there is no specific treatment that proves effective. Treatment focuses on managing symptoms and minimizing disability to the extent possible.
• Canes, braces, walkers and motorized wheelchairs can be useful in mobility problems.
• Careful monitoring of cardiac and respiratory functions that can lead to early treatment of these problems with a cardiac pacemaker or respirator laptop.
• Medications and other treatments for constipation and other ailments of the digestive tract.
• Cataract surgery and surgery for drooping eyelids can significantly improve the view.
• New drugs to treat excessive sleepiness can make life easier for the person with Myotonic dystrophy and your family.
Early intervention in children with congenital myotonic dystrophy is crucial. Hearing abnormalities and vision should be diagnosed and treated promptly. Surgery to correct the lack of coordination of the muscles of the eyes and special education can have great influence on the subsequent success of the child’s life.

The myotonic dystrophy (MD), Also known as myotonic dystrophy type 1, MD1 is a hereditary disease multisystem chronic, slowly progressive and highly variable heritability can happen at any time of life from birth to old age. It is characterized by a reduction in muscle mass (myotonic muscular dystrophy) Cataracts posterior subcapsular iridescent (lens opacity) defects in cardiac impulse conduction, changes endocrine and myotonia (Difficulty relaxing a muscle). It is curious that the age of onset is highly variable, decreases with successive generations. Thus the disease shows an age of onset dwindling, a phenomenon called anticipation. There are two classifications of myotonic dystrophy, each having different associated myotonic dystrophy symptoms.

Myotonic dystrophy classification

Myotonic dystrophy is the most common form of adult onset of muscular dystrophy and the second most common form of skeletal muscle disease after Duchenne muscular dystrophy. Currently there are two kinds of diabetes onset in adulthood: Myotonic dystrophy type 1 (MD1), the actual known as Steinert’s disease and myotonic dystrophy type 2 (MD2), commonly referred to as PROMMA or proximal myotonic myopathy. Both are identified by DNA analysis. The congenital myotonic dystrophy form can seriously affect babies and has a form of childhood-onset. Researchers suspect that there are more forms of myotonic dystrophy (MD3, MD4, MDX).

Differences between MD1 and MD2

Muscle biopsy from a patient with myotonic muscular dystrophy 2 showing mild changes and grouping of atrophic red fibers. Immunohistochemical analysis of myosin type-1 or “slow”
Although both diseases are considered as slowly developing degenerative disease, type 2 diabetes is generally milder than myotonic dystrophy 1. The severe congenital form that affects babies in MD1 has not been found in MD2 and rarely published medical literature juvenile onset of this form. The expansion of trinucleotide of MD2 is considerably longer in MD2 than in MD1, ranging from 75 to more than 11000 repeats. Unlike MD1, the size of trinucleotide expansions in the DNA does not seem to make no difference in age of onset or disease severity in MD2. It seems to be less significant in type 2 standard and revisions relate only to produce a slight advance in the latter case.

The myotonic dystrophy is a disease transmitted genetics where he is involved a pattern of autosomal dominant, Meaning that a mutant gene from one parent will result in this condition. There is a 50% chance of receiving the affected parent MD. In MD1, the gene affected is MDPK (myotonic dystrophy protein kinase that encodes myosin kinase expressed in skeletal muscles. This gene is located on the long arm of chromosome 19. The MD2 is similarly caused by a defect ZNF9 gene in chromosome 3.

Myotonic dystrophy is one of the severe trinucleotide repeat disorders. Certain areas of DNA have repeated sequences of two or three Nucleotide. In MD1, there is a triplet repeat cytosine – thymine – guanine (CTG) in the MDPK gene. The number of repeats varies greatly from person to person, but on average in a healthy subject is between 5 and 37. Sometimes when repetitive DNA sequences are replicated in cell division cellular machinery adds an extra copy of the triplet repeat sequence. So there are 37 triple repeats in the MDPK gene, the sequence begins to become unstable and landslides are more likely to occur. The affected population of MD1 are over 50 and sometimes as many as 2000 iterations.

The result is that the repeat size of an individual with MD1 will become larger as they age. This explains the phenomenon of anticipation and each child of an affected adult will have greater expansion than its predecessor due to landslides during the gametogenesis.

Individuals with larger expansions have the disorder earlier and more severe phenotype. The repeat expansion for MD2 is much larger than in MD1, ranging from 75 to more than 11,000 repetitions. Except MD1, the size of the repeated DNA expansion does not appear to be significant in the entrance age or disease severity in MD2. The advance appears to be less significant in T2MD and half reported current reviews anticipation as a feature of MD2.

Myotonic dystrophy symptoms

Affected individuals have a typical “hatchet-shaped face” the result of atrophy of the temporalis muscles, masseter, and facials.

Men often have frontal alopecia. The muscles of the neck and distal members are affected early.
There is weakness of the extensors of the wrist, fingers and intrinsic hand muscles. The muscles that allow dorsiflexion of the ankle are affected causing a foot drop. The proximal muscles are usually preserved, although many patients have involvement of quadriceps. There is involvement of muscles of the palate, throat and tongue that can cause dysarthria, nasal voice and swallowing problems. Many patients have weak respiratory muscles, causing respiratory failure.

Myotonia may be evident from the age of 5, asking the patient to close his hand tightly, and then relax, which occurs slowly.

The cardiac manifestations are common, mainly first-degree AV block, including electrical problems and mitral prolapse. Complete blockages can occur, causing sudden death of the patient.

Made a vehement call authorities and medical scientists of the Social Security Fund (CCSS), the Costa Rican population to join forces and reduce the impact of diabetes.

As revealed today, Dr. Eduardo Doryan Garron, chief executive of the CCSS, the disease is affecting thousands of Costa Rican families and it is urgent to curb it by practicing healthy lifestyles.

It is estimated that in Costa Rica two people a day die because of diabetes. In 2008, the National Institute of Statistics and Census (INEC) reported 742 deaths from this cause which represents 4.2 percent of total deaths registered during this period in the country.

Type 1 diabetes facts and statistics

Dr. Doryan Garron said that according to a study by the Actuarial and Statistical Area data from the CCSS, in 2008, the institution provided 400,297 consultations due to diabetes, 15 percent more than those in 2004.

Institutional investment to tackle diabetes in that year amounted to ¢ 20.559 million by way of consultation, care in the emergency services, hospitalizations and disabilities. Only a hypoglycemic drug purchase as the acquisition of insulin, the CCSS spent $ 5.1 million to maintain daily treated 175,678 patients.

Type 1 diabetes facts: According to information issued by the Statistics Area of the CCSS, the female population is most affected with the disease, since in the reference period were 101,639 outpatients and 26,547 emergency room more often than men. The behavior was similar in expenditures since they had more than 276 discharges them.

A third of patients hospitalized with diabetes, he had to perform any special procedures such as amputations of the lower and upper abdominal surgeries in the region, x-ray soft tissue of the face, head and neck, among others.

The study by the Actuarial Department also reveals that 87 percent of deaths occurring in Costa Rica were in people whose age was about 50 years and is estimated to lose a total of 7211 years of life due to this cause death.

In Costa Rica about 90 percent of diabetes cases are type 2 and 10 percent have type 1 diabetes or juvenile diabetes. Indeed, one of the great efforts made by Costa Rica is that 100 percent of patients with type 1 diabetes under control in the National Children’s Hospital.

Now the concern of the experts is that type two diabetes is appearing in increasingly younger population, including children. At this time, Children’s Hospital has treated 35 children diagnosed with type 2 diabetes, as revealed Dr Orlando Jaramillo, an endocrinologist at the medical center.

For his part, Dr. Carlos Arguedas Chaverri, Section Chief of Medicine, Mexico Hospital and Dr. Eduardo Rodriguez Caldera, head of the Endocrinology Service of Hospital San Juan de Dios, were emphatic on the urgency of the Costa Rican population control weight, not smoke and have adequate nutritional habits.

It is necessary for obese people, those with a family history of diabetes, during pregnancy women who have had diabetes and those who have had children whose weight exceeded four kilos, perform a screening to see if they are diabetic.

It is important, according to experts, diabetic patients to remember that control of the disease has three pillars: the constancy of physical activity, diet and discipline in the use of medications. If any of these three pillars failure of disease control also fails.

Type 1 diabetes facts: Type I diabetes is called juvenile diabetes. Occurs in children, youth and young adults. It is a chronic condition that needs attention. It is important that parents teach their child to live with the disease and be your partner during their lifetime. It is important to monitor your child and the symptoms do not always appear before diagnosed.

Type 1 diabetes facts for kids

If you notice your child has any of the following symptoms, we suggest you visit your doctor: feeling tired for no apparent reason, very hungry, being very thirsty, frequent urination, weight loss for no apparent reason, having blurred vision, loss of feeling or tingling in the feet, dry mouth and skin, fruity breath odor, headache, among others.

The Diabetes has become in recent years in an alarming global problem. According to the International Diabetes Foundation, the number of people diagnosed has increased over the past 20 years from 30 to over 246 million, which represents approximately 7.3% of the population. EE. UU. has the highest percentage. In the Middle East and in some Caribbean countries, between 12 and 20% of the population suffer from diabetes.

Type 1 diabetes facts

There are many theories about the causes of this increase in diabetes cases. One reason is that while in the U.S.. UU. have collected data on diabetes for many years in many other countries have just begun, so far, to realize the importance of these data and how diabetes affects the population. This explains in part the remarkable increase in the number of cases that now are known, but this is not the only reason.

Lifestyle plays a fundamental role in the etiology of diabetes and is the reason why the Diabetes type 2 contributes at least 90 to 95% the increase in diabetes in the population. The adoption of Western lifestyles in developing countries has increased and changed the pattern of everyday life in many countries. Lack of time, which is determined by the increased pressure in the workplace, has meant a substantial reduction in time should be devoted to preparing healthy meals. This also helps to take a less active lifestyle and, when combined with inactivity, unhealthy foods and nutrients, raises the risk for type 2 diabetes. Type 1 diabetes facts: Factors Genethics are certainly also relevant in the onset of Type 1 Diabetes but only contributes between 5 and 10% of cases worldwide.

Type 1 diabetes facts and statistics

Some interesting facts about diabetes:

• Type 1 diabetes facts and statistics, Currently there are worldwide more than 260 million diabetics.
• If the current growth rate continues to grow in the same way, by 2025 more than 418 million people with diabetes.
• Are diagnosed each year 65,000 new cases of diabetes.
• It’s been 80 years since the discovery of insulin, but there are still many people around the world who can not access it regularly or can not afford it at all.
• Diabetes can damage many organs (including kidneys), peripheral nerves, blood vessels, eyes (and even cause blindness) and can also cause the loss of members of the lower limbs due to circulation problems.
• Type 2 diabetes can be prevented in approximately 80% of cases and therefore prevention should occupy a high priority in the fight against diabetes worldwide.
• More than half of people with diabetes do not know.
• Also read type 1 diabetes fact for kids

The current diet is not enough food usually includes raw and has more than enough food handled. The result is an enzyme depletion effects on our health.

The use of digestive enzymes to treat diseases is very old. The Mayans and other peoples applied papaya leaves, which contain an enzyme called papain, in malignant ulcers. But it was in the early twentieth century when German scientists discovered that certain dysfunctions of the body were related to the activity of enzymes. The pancreatic juice rich in enzymes, then came into use for the treatment of cancer. Today, the enzyme therapy, the name given to the therapeutic use of enzymes, is increasingly used in treatments to improve digestion, eliminate viruses, boost immunity, speed healing of wounds and suppress the inflammatory response.

There are two different kinds of enzymes and the digestive, to help us break down and assimilate nutrients, and metabolic enzymes, which play a fundamental role in maintaining life processes. But in addition, raw foods we also provide enzymes that help us digest food.

The digestive organs such as the pancreas and liver are responsible for producing most of the digestive enzymes, and the rest should be provided by uncooked fresh foods like fruits, raw vegetables, sprouts, seaweed, seeds and nuts, dairy products pasteurized and enzyme supplements. When the diet is low in enzymes, the pancreas has to make a greater effort to produce digestive enzymes. If the pancreas is overworked, there is a deficiency of metabolic enzymes vital for the development of all cellular functions.

Enzymatic Therapy works by improving digestive function and ensures good digestion and assimilation of nutrients. Provide insufficient digestion conditions prone to the disease, such as undigested food properly promote a harmful intestinal flora, proteins putrefy, ferment carbohydrates and fats become rancid. This favors the formation of toxic compounds such as nitrosamines and ammonia, known carcinogens. Also, undigested proteins, called peptides, can enter the systemic circulation, where the immune system recognizes as foreign and attacks them, resulting in allergic reactions.

Digestive enzymes meals eaten outside work against the disease more directly, attacking, for example, the coat protein of cancer cells, tumors or virus destroying the harmful immune complexes by dissolving blood clots and reduce inflammation. Pancreatic enzymes have been used to detect antigens on the surface of cancer cells, allowing the immune system identify and destroy them, and also to stimulate immune function. Besides proteolytic, enzymes degrade the cover of cancer cells which are composed of proteins and thus get the chemotherapy work more effectively and at lower doses.

Furthermore, clinical studies have demonstrated the positive effects of enzymatic therapy against herpes zoster and warts. The virus, like cancer cells are covered by a protein coat that can be digested by proteolytic enzymes. Another promising area for enzymatic therapy is autoimmune diseases. These arise when the immune system attacks its own tissues and organs, creating immune complexes that cause injury and inflammation. These include multiple sclerosis, rheumatoid arthritis, juvenile diabetes, lupus or colitis. The enzyme therapy in these cases acts by destroying the immune complexes, preventing their formation and reduce inflammation.

The enzymatic therapy is also being used in vascular disease to dissolve blood clots and prevent blood from clotting, so inhibiting the formation of deposits in the arteries and reduce blood thickness. It is indicated for both cases of phlebitis, thrombosis, atherosclerosis and venous insufficiency.

Why it matters enzyme supplements?

Taken with food, enzymes improve digestion of proteins, carbohydrates and fats and are described in the following treatments:

* Obesity, cystic fibrosis, pancreatic enzymes, lipase, ox bile

* Flatulence, bloating, pancreatic enzymes, amylase.

* Asthma, eczema, allergies, irritable bowel syndrome: pepsin, betaine hydrochloride, pancreatic enzymes

Taken between meals are listed at:

* AIDS: pancreatin, papain, lipase, amylase, bromelain, trypsin and chymotrypsin, with bioflavonoids.

* Warts, herpes zoster: trypsin, chymotrypsin, protease.

* Cancer pancreatin, pepsin, betaine hydrochloride, bromelain, papain, trypsin, qumiotripsina, lipase, amylase

* Benign breast tumors: proteolytic enzymes along with vitamin E.

* Esclerois multiple: pancreatin with essential fatty acids.

Finally, proteolytic enzymes taken between meals can improve vascular disease, treat wounds, reduce inflammation, and improve arthritis and rheumatism.

Fresh, raw foods

The enzymes found in fresh raw foods and are very sensitive to heat, are destroyed at temperatures from 30 ° C. Fried food is, in this sense, one of the worst methods of cooking as they used very high temperatures. The same applies to pasteurization, canning and microwave for high temperatures.

A diet of cooked and processed foods forces the pancreas to secrete more digestive enzymes, and therefore spend less metabolic energy to produce enzymes which eventually leads to enzyme depletion.

It is however necessary to follow a strict raw food diet, but it is important to include everyday foods rich in enzymes, denatured and live as fruits and vegetables, sprouts, seaweed, seeds, nuts and unpasteurized dairy products. A comprehensive food, biological, rich in vegetables and fruits is itself rich in minerals and vitamins, nutrients for the body to produce its own enzymes more efficiently.

By Elena Perea

Orthomolecular nutritionist

Some people want to do a DNA paternity test during pregnancy. Know that this is possible but not without risk.

Indeed, a paternity test during pregnancy means that you take cells directly into the womb, which can cause miscarriages. It’s the only way I would therefore strongly discourage you from this type of testing because you can make from the birth of the child and without any risk to his health.

Finally, if you still want to do a paternity test before birth, know that you’ll have to go directly in the laboratory to take a DNA sample of the baby because you can not do it alone (because the cells of the child for the test are obtained from a syringe, where the risk of miscarriage)